Hodgkin disease

Hodgkin disease is a potentially curable malignant lymphoma with distinct histology, biologic behavior, and clinical characteristics.

SYMPTOMS:

Asymptomatic lymphadenopathy

unexplained weight loss

fever

night sweats

classic Pel-Ebstein fever is observed

Chest pain

cough

shortness of breath,

pruritus

Pain at sites of nodal disease by drinking alcohol is specific for Hodgkin lymphoma

Back or bone pain occurs rarely

SIGNS:

Palpable painless lymphadenopathy occurs in the cervical area as rubbery adenopathy

Splenomegaly and/or hepatomegaly

SVC syndrome may develop in patients with massive mediastinal lymphadenopathy

Hodgkin lymphoma–associated anemia is most commonly the anemia of chronic disease.